Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.43 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.43 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.43 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | RAD1 | O60671 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601738 | 0.85 | RAD51 (0.54) | NT5EHPGDRAD51CA1CA2 | |
| SCHEMBL29356717 | 0.84 | RAD51 (0.56) | NT5EENPP2HPGDRAD51KMT2A | |
| SCHEMBL670637 | 0.84 | RAD51 (0.56) | NT5EENPP2HPGDRAD51KMT2A | |
| SCHEMBL455775 | 0.84 | RAD51 (0.56) | NT5EENPP2HPGDRAD51KMT2A | |
| SCHEMBL455776 | 0.84 | RAD51 (0.56) | NT5EENPP2HPGDRAD51KMT2A | |
| SCHEMBL10703629 | 0.83 | NT5E (0.65) | NT5EHPGDALOX12L3MBTL1KIF11 | |
| SCHEMBL22003965 | 0.83 | RAD51 (0.48) | NT5EENPP2GUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL7744489 | 0.82 | RAD51 (0.55) | NT5EENPP2RAD51KMT2AMEN1 | |
| SCHEMBL6815530 | 0.82 | RAD51 (0.55) | NT5EENPP2RAD51CA1CA2 | |
| SCHEMBL8653989 | 0.82 | RAD51 (0.55) | NT5EENPP2RAD51KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883922-A1 | DISULFONATE STILBENES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES | Université de Nantes (FR) | 2021-09-29 | — | — | EP | disclosed |