Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAD1 | O60671 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670637 | 1.00 | RAD51 (0.56) | RAD51NT5EALDH1A1TSHRCYP2C19 | |
| SCHEMBL455776 | 1.00 | RAD51 (0.56) | RAD51NT5EALDH1A1TSHRCYP2C19 | |
| SCHEMBL29356717 | 1.00 | RAD51 (0.56) | RAD51NT5EALDH1A1TSHRCYP2C19 | |
| SCHEMBL6815520 | 0.98 | RAD51 (0.55) | RAD51NT5EALDH1A1TSHRCYP2C19 | |
| SCHEMBL7744489 | 0.98 | RAD51 (0.55) | RAD51NT5EALDH1A1TSHRCYP2C19 | |
| SCHEMBL8653989 | 0.98 | RAD51 (0.55) | RAD51NT5EALDH1A1TSHRCYP2C19 | |
| SCHEMBL10633178 | 0.98 | RAD51 (0.55) | RAD51NT5EALDH1A1TSHRCYP2C19 | |
| SCHEMBL9818822 | 0.98 | RAD51 (0.58) | RAD51NT5EALDH1A1TSHRCYP2C19 | |
| SCHEMBL6815530 | 0.98 | RAD51 (0.55) | RAD51NT5EALDH1A1TSHRCYP2C19 | |
| SCHEMBL7744491 | 0.98 | RAD51 (0.55) | RAD51NT5EALDH1A1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190000791-A1 | ISOTHIOCYANATOSTILBENES AS A NOVEL METHOD AND PRODUCT FOR TREATING CANCER | Board of Supervisors for the University of Louisiana System | 2019-01-03 | — | — | US | claimed |
| CN-108654686-A | A kind of catalyst of photocatalytic reduction of carbon oxide and preparation method thereof | 北京化工大学 | 2018-10-16 | — | — | CN | claimed |
| CN-108017565-A | Hydrogenating reduction method prepares DSD acid | 江苏淮河化工有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-105315177-A | Synthesis process of DSD acid | ZHEJIANG QECOTE ENVIRONMENTAL TECHNOLOGY CO LTD | 2016-02-10 | — | — | CN | claimed |
| CN-103642490-B | D (Donor)/A (Acceptor) type stilbene molecule co-intercalated hydrotalcite composite photoelectric material and preparation method thereof | UNIV BEIJING CHEMICAL | 2014-12-31 | — | — | CN | claimed |
| CN-103642490-A | D (Donor)/A (Acceptor) type stilbene molecule co-intercalated hydrotalcite composite photoelectric material and preparation method thereof | UNIV BEIJING CHEMICAL | 2014-03-19 | — | — | CN | claimed |
| EP-0953153-B1 | METHOD OF DIAGNOSING AND TREATING GLIOMAS | UAB RESEARCH FOUNDATION (US) | 2013-07-10 | — | — | EP | claimed |
| US-8114432-B2 | Ion transport mechanism interference agent is capable of interfering with the cellular mechanisms of lens epithelial cells while leaving other ocular cells unharmed | Zhang, Jin Jun (CN) | 2012-02-14 | — | — | US | claimed |
| US-7985405-B2 | Ion transport mechanism interference agent is capable of interfering with the cellular mechanisms of lens epithelial cells while leaving other ocular cells unharmed | ZHANG, JIN JAN (CN) | 2011-07-26 | — | — | US | claimed |
| US-20100168030-A1 | Methods and compositions for treatment of organophosphate-caused pathology | ARMY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2010-07-01 | — | — | US | claimed |
| EP-0026154-B1 | PROCESS FOR PREPARING 4,4'-DINITROSTILBENE-2,2'-DISULFONIC ACID AND ITS SALTS AND ITS USE | CIBA-GEIGY AG (CH) | 1983-06-29 | — | — | EP | claimed |
| US-4348335-A | Process for the partial reduction of polynitrated diaryl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | claimed |
| EP-0026154-A1 | Process for preparing 4,4'-dinitrostilbene-2,2'-disulfonic acid and its salts and its use | CIBA-GEIGY AG (CH) | 1981-04-01 | — | — | EP | claimed |
| EP-0018541-A1 | Process for the preparation of 4-nitrotoluene-2-sulfonic acid | BAYER AG (DE) | 1980-11-12 | — | — | EP | claimed |
| US-4217304-A | Continuous reduction process | CIBA-GEIGY AG (CH) | 1980-08-12 | — | — | US | claimed |
| US-4179476-A | Semi-continuous process for obtaining amino compounds | CIBA-GEIGY CORPORATION (US) | 1979-12-18 | — | — | US | claimed |
| US-4070395-A | CATATALYTIC HYDROGENATION, RANEY NICKEL, DICYANDIAMIDE | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1978-01-24 | — | — | US | claimed |
| US-4051177-A | PROCESS FOR THE PREPARATION OF UNSATURATED AMINO COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | claimed |
| US-4002673-A | GROUP VIII METAL SULFIDE AS HYDROGENATION CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | claimed |
| US-3989743-A | Process for the preparation of 4,4'-diaminostilbene-2,2'-disulphonic acid | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190000791-A1 | ISOTHIOCYANATOSTILBENES AS A NOVEL METHOD AND PRODUCT FOR TREATING CANCER | SI, PCMT1, HDAC8 | RAD51 4231/4885NT5E 4493/4885ALDH1A1 819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.