Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 7/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23853619 | 0.96 | TNF (0.49) | TNFCNR2CNR1CYP4F2CYP4A11 | |
| SCHEMBL23852674 | 0.89 | TNF (0.50) | TNFCNR2CNR1CYP4F2CYP4A11 | |
| SCHEMBL23853379 | 0.85 | CNR2 (0.39) | CNR2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL23852583 | 0.84 | TNF (0.54) | TNFCNR2CNR1CYP4F2CYP4A11 | |
| SCHEMBL23850522 | 0.78 | MEN1 (0.45) | TNFCNR2 | |
| SCHEMBL3024871 | 0.75 | EPHX2 (0.42) | TNFCNR2 | |
| SCHEMBL29225350 | 0.74 | EPHX2 (0.44) | CNR2CNR1ALDH1A1 | |
| SCHEMBL23850165 | 0.74 | MEN1 (0.49) | TNFCNR2ALDH1A1 | |
| SCHEMBL29903004 | 0.74 | CNR2 (0.43) | TNFCNR2 | |
| SCHEMBL29225365 | 0.71 | TSHR (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883931-A1 | HETEROCYCLIC COMPOUNDS AND MEDICAL USE THEREOF | Fondazione Telethon (IT) | 2021-09-29 | — | — | EP | disclosed |