Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340560 | 0.88 | GID4 (0.46) | GID4KDM4EALDH1A1DRD2DRD1 | |
| SCHEMBL21616753 | 0.88 | GID4 (0.46) | GID4KDM4EALDH1A1DRD2DRD1 | |
| SCHEMBL17193124 | 0.79 | GID4 (0.42) | GID4KDM1AADRA2A | |
| SCHEMBL17192148 | 0.79 | GID4 (0.42) | GID4ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL17192147 | 0.79 | GID4 (0.42) | GID4ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL4206685 | 0.79 | GID4 (0.42) | GID4KDM4EALDH1A1DRD2DRD1 | |
| SCHEMBL13974016 | 0.79 | KMT2A (0.44) | GID4DRD2DRD1DRD4DRD5 | |
| SCHEMBL13616719 | 0.79 | KMT2A (0.44) | GID4DRD2DRD1DRD4DRD5 | |
| SCHEMBL12270073 | 0.79 | GID4 (0.42) | GID4ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL29983834 | 0.79 | GID4 (0.42) | GID4KDM1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883938-A1 | INHIBITORS OF ARGINASE | Praxis Biotech LLC (US) | 2021-09-29 | — | — | EP | disclosed |