Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.55 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.55 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.55 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.55 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009625 | 0.92 | MAPT (0.62) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL16363758 | 0.90 | ENPP2 (0.67) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL168451 | 0.90 | ENPP2 (0.49) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL11625123 | 0.90 | ENPP2 (0.49) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL168452 | 0.90 | ENPP2 (0.49) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL2221705 | 0.89 | SNCA (0.50) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL1447494 | 0.89 | ENPP2 (0.48) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL2221661 | 0.89 | ENPP2 (0.48) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL1169592 | 0.89 | ENPP2 (0.48) | ENPP2TNNI3TNNT2TNNC1HKDC1 | |
| SCHEMBL9436833 | 0.86 | TNNI3K (0.50) | ENPP2TNNI3TNNT2TNNC1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883922-A1 | DISULFONATE STILBENES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES | Université de Nantes (FR) | 2021-09-29 | — | — | EP | disclosed |