SCHEMBL23854819

SCHEMBL23854819

NC(CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACE P12821 7/20 0.47
REN P00797 4/20 0.47
KDM4E B2RXH2 1/20 0.47
F2 P00734 1/20 0.47
LMNA P02545 1/20 0.47
LTA4H P09960 1/20 0.47
MAPT P10636 1/20 0.47
PEPD P12955 1/20 0.47
ALOX15 P16050 1/20 0.47
PTGS1 P23219 1/20 0.47
HTR2A P28223 1/20 0.47
PTGS2 P35354 1/20 0.47
HRH1 P35367 1/20 0.47
THPO P40225 1/20 0.47
PMP22 Q01453 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ACE2 Q9BYF1 1/20 0.47
CAPN1 P07384 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23091321 1.00 ACE (0.47) ACERENKDM4EF2LMNA
SCHEMBL23091320 1.00 ACE (0.47) ACERENKDM4EF2LMNA
SCHEMBL29379676 0.92 ACE (0.54) ACERENKDM4EF2LMNA
SCHEMBL31547785 0.91 ACE (0.53) ACERENKDM4EF2LMNA
SCHEMBL29434627 0.90 CAPN1 (0.51) ACERENKDM4EF2LMNA
SCHEMBL29371779 0.89 ACE (0.48) ACERENKDM4EF2LMNA
SCHEMBL29722270 0.89 ACE (0.48) ACERENKDM4EF2LMNA
SCHEMBL30522298 0.89 CAPN1 (0.51) ACERENKDM4EF2LMNA
SCHEMBL29894803 0.88 ACE (0.52) ACERENKDM4EF2LMNA
SCHEMBL30165187 0.88 F2R (0.47) ACERENKDM4EF2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250241872-A1 AFFINITY MEDICANT CONJUGATE Illudent, Inc. (US) 2025-07-31 US disclosed
US-12280021-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2025-04-22 US disclosed
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2023-11-23 US disclosed
US-11576876-B2 Affinity Medicant Conjugate AF CHEMICALS, LLC (US) 2023-02-14 US disclosed
US-20220133649-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2022-05-05 US disclosed
US-20210299063-A1 AFFINITY MEDICANT CONJUGATE AF CHEMICALS, LLC (US) 2021-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12280021-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A ACE 930/4885REN 1894/4885KDM4E 300/4885
US-20210299063-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A ACE 930/4885REN 1894/4885KDM4E 300/4885
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A ACE 930/4885REN 1894/4885KDM4E 300/4885
US-20220133649-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A ACE 930/4885REN 1894/4885KDM4E 300/4885
US-11576876-B2 Affinity Medicant Conjugate FCER2, HDGF, FCGR2A ACE 930/4885REN 1894/4885KDM4E 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.