Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23856487 | 0.85 | SERPINE1 (0.38) | — | |
| SCHEMBL19330417 | 0.83 | CYP2D6 (0.42) | CYP2D6CYP2C19 | |
| SCHEMBL23857316 | 0.80 | CYP3A4 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL18340836 | 0.79 | CYP2D6 (0.38) | CYP2D6CYP2C19 | |
| SCHEMBL30554097 | 0.79 | CYP2D6 (0.38) | CYP2D6CYP2C19 | |
| SCHEMBL18990458 | 0.79 | CYP2D6 (0.38) | CYP2D6CYP2C19 | |
| SCHEMBL19330741 | 0.78 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL18990213 | 0.78 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL18990212 | 0.78 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL19330547 | 0.78 | CYP2D6 (0.37) | CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126855-B1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | HOFFMANN LA ROCHE (CH) | 2024-04-24 | — | — | EP | disclosed |
| US-20230167127-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-06-01 | — | — | US | disclosed |
| EP-4126855-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021190727-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2021-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167127-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | LTB4R, C5, C3AR1 | CYP2D6 378/4885CYP2C19 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.