Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27097004 | 1.00 | SYK (0.58) | SYKL3MBTL1HTTERBB2EGFR | |
| SCHEMBL159323 | 0.85 | SYK (0.78) | SYKL3MBTL1ERBB2EGFRERBB3 | |
| SCHEMBL29638125 | 0.85 | SYK (0.78) | SYKL3MBTL1ERBB2EGFRERBB3 | |
| Ammonia Solution, Strong SCHEMBL23859934 | 0.84 | SYK (0.76) | SYKL3MBTL1ERBB2EGFRERBB3 | |
| Hydrochloric Acid SCHEMBL6239858 | 0.84 | SYK (0.76) | SYKL3MBTL1HTTERBB2EGFR | |
| SCHEMBL27096805 | 0.78 | MAPT (0.53) | L3MBTL1HTTSMN1; SMN2PKMRAB9A | |
| SCHEMBL5699048 | 0.76 | SYK (0.53) | SYKL3MBTL1ERBB2EGFRMAOA | |
| SCHEMBL4028096 | 0.74 | SYK (0.54) | SYKL3MBTL1HTTERBB2EGFR | |
| SCHEMBL17601189 | 0.74 | SYK (1.00) | SYKL3MBTL1ERBB2EGFRHRH1 | |
| SCHEMBL30623239 | 0.74 | SYK (1.00) | SYKL3MBTL1ERBB2EGFRHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |