Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 16/20 | 0.57 |
| ▸ | EGFR | P00533 | 13/20 | 0.57 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.57 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | STK4 | Q13043 | 1/20 | 0.46 |
| ▸ | STK3 | Q13188 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27751267 | 0.87 | ERBB2 (0.58) | ERBB2EGFRERBB3ERBB4SYK | |
| SCHEMBL6979593 | 0.86 | ERBB2 (0.59) | ERBB2EGFRERBB3ERBB4SYK | |
| SCHEMBL6957850 | 0.83 | ERBB2 (0.56) | ERBB2EGFRERBB3ERBB4SYK | |
| SCHEMBL22967411 | 0.83 | ERBB2 (0.56) | ERBB2EGFRERBB3ERBB4SYK | |
| SCHEMBL20548962 | 0.82 | ERBB2 (0.59) | ERBB2EGFRERBB3ERBB4SYK | |
| SCHEMBL9719782 | 0.82 | ERBB2 (0.53) | ERBB2EGFRERBB3ERBB4SYK | |
| SCHEMBL29638125 | 0.81 | SYK (0.78) | ERBB2EGFRERBB3ERBB4SYK | |
| SCHEMBL159323 | 0.81 | SYK (0.78) | ERBB2EGFRERBB3ERBB4SYK | |
| SCHEMBL9719862 | 0.81 | ERBB2 (0.74) | ERBB2EGFRERBB3ERBB4SYK | |
| SCHEMBL31084744 | 0.81 | ERBB2 (0.74) | ERBB2EGFRERBB3ERBB4SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195206-A1 | POLYMORPHIC FORMS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |