SCHEMBL2386153

SCHEMBL2386153

CC(O[Si](C)(C)C(C)(C)C)C(C)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2386156 1.00
Butylamine SCHEMBL8431965 0.84 CA2 (0.33)
SCHEMBL18013521 0.81
SCHEMBL17909994 0.80 SLC7A5 (0.41)
SCHEMBL14062501 0.80 SLC7A5 (0.41)
SCHEMBL12769953 0.80 SMN1; SMN2 (0.33)
SCHEMBL18157220 0.80
SCHEMBL12769955 0.80 SMN1; SMN2 (0.33)
SCHEMBL2686923 0.78 TP53 (0.32)
SCHEMBL840126 0.78 TP53 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110237814-A1 NOVEL RUTHENIUM CARBONYL COMPLEX HAVING TRIDENTATE LIGAND, ITS PRODUCTION METHOD AND USE TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-09-29 US disclosed
EP-0269236-B1 PROCESS FOR SYNTHESIS OF A CHIRAL AZETIDINONE MERCK & CO. INC. (US) 1991-04-03 EP disclosed
EP-0269236-A1 Process for synthesis of a chiral azetidinone MERCK & CO. INC. (US) 1988-06-01 EP disclosed