SCHEMBL2386271

SCHEMBL2386271

CCCCCCCCCCCCCCCCCC(=O)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 6/20 0.74
CASP2 P42575 1/20 0.57
GNAI3 P08754 1/20 0.56
GNAO1 P09471 1/20 0.56
GNAI1 P63096 1/20 0.56
FAAH O00519 4/20 0.55
DPP7 Q9UHL4 1/20 0.55
EPHX2 P34913 3/20 0.55
NAAA Q02083 1/20 0.54
SLC6A5 Q9Y345 2/20 0.54
DNM1 Q05193 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31734852 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1
SCHEMBL31358862 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1
SCHEMBL15986104 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1
SCHEMBL31711351 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1
SCHEMBL13855547 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1
SCHEMBL17392871 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1
SCHEMBL1243678 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1
SCHEMBL358468 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1
SCHEMBL308741 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1
SCHEMBL20162089 1.00 NOD1 (0.74) NOD1CASP2GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0615522-B1 MURAMYL COMPOUNDS FOR TREATMENT OF SEPTIC SHOCK PEPTECH UK LTD (GB) 1999-09-22 EP claimed
WO-1998009989-A1 THE USE OF MURAMYLPEPTIDES IN THE TREATMENT OF MYELOSUPPRESSED OR OTHERWISE IMMUNOCOMPROMISED STATES PEPTECH (UK) LIMITED (GB) 1998-03-12 WO claimed
CN-1162920-A Use of muramyl peptide compounds PEPTECH UK LTD (GB) 1997-10-22 CN claimed
EP-0782454-A1 USE OF MURAMYL PEPTIDE COMPOUNDS PEPTECH (UK) (GB) 1997-07-09 EP claimed
EP-0768888-A1 USE OF MURAMYL PEPTIDE COMPOUNDS PEPTECH (UK) LIMITED (GB) 1997-04-23 EP claimed
EP-0722332-A1 COMPOUNDS FOR MEDICINAL USE PEPTECH (UK) LIMITED (GB) 1996-07-24 EP claimed
WO-1996009063-A1 USE OF MURAMYL PEPTIDE COMPOUNDS PEPTECH(UK) LIMITED (GB) 1996-03-28 WO claimed
WO-1996001645-A1 USE OF MURAMYL PEPTIDE COMPOUNDS PEPTECH(UK) LIMITED (GB) 1996-01-25 WO claimed
EP-0689449-A1 THERAPEUTICAL COMPOSITIONS FOR USE IN HUMANS, CHARACTERISED BY A COMBINATION OF A MURAMYL PEPTIDE AND A CYTOKINE VACSYN S.A. (FR) 1996-01-03 EP claimed
WO-1995010293-A1 COMPOUNDS FOR MEDICINAL USE PEPTECH (UK) LIMITED (GB) 1995-04-20 WO claimed
WO-1994021275-A1 THERAPEUTICAL COMPOSITIONS FOR USE IN HUMANS, CHARACTERISED BY A COMBINATION OF A MURAMYL PEPTIDE AND A CYTOKINE VACSYN S.A. (FR) 1994-09-29 WO claimed
WO-1993010148-A1 MURAMYL COMPOUNDS FOR TREATMENT OF SEPTIC SHOCK PEPTECH (UK) LIMITED (GB) 1993-05-27 WO claimed
EP-0021367-B1 MURAMYLDIPEPTIDE DERIVATIVES, PROCESS FOR PREPARING SAID COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS DAIICHI SEIYAKU CO., LTD. (JP) 1983-04-06 EP claimed
EP-0021367-A1 Muramyldipeptide derivatives, process for preparing said compounds and pharmaceutical compositions containing said compounds DAIICHI SEIYAKU CO., LTD. (JP) 1981-01-07 EP claimed
JP-63093724-A None JP disclosed
US-12552743-B2 Oligonucleotide compositions and methods of use thereof WAVE LIFE SCIENCES LTD. (SG) 2026-02-17 US disclosed
EP-4684030-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2026-01-28 EP disclosed
EP-0139481-A2 Surface modification using N-acyl lysines AJINOMOTO CO., INC. (JP) 1985-05-02 EP disclosed
EP-0021367-B1 MURAMYLDIPEPTIDE DERIVATIVES, PROCESS FOR PREPARING SAID COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS DAIICHI SEIYAKU CO., LTD. (JP) 1983-04-06 EP disclosed
EP-0021367-A1 Muramyldipeptide derivatives, process for preparing said compounds and pharmaceutical compositions containing said compounds DAIICHI SEIYAKU CO., LTD. (JP) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552743-B2 Oligonucleotide compositions and methods of use thereof NSUN3, NSUN2, SNRPA1 NOD1 4241/4885CASP2 4449/4885GNAI3 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.