Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | IL1B | P01584 | 2/20 | 0.39 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.39 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP11A1 | P05108 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21281328 | 0.81 | CYP19A1 (0.35) | CRBNDDB1CYP19A1CYP3A4CYP17A1 | |
| SCHEMBL20459229 | 0.75 | CRBN (0.43) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL23979831 | 0.73 | CRBN (0.46) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL23979970 | 0.73 | CRBN (0.46) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL23979944 | 0.73 | CRBN (0.46) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL23979453 | 0.70 | CRBN (0.47) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL23979978 | 0.70 | CRBN (0.47) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL23979565 | 0.70 | CRBN (0.47) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL5958850 | 0.69 | CRBN (0.50) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL19310143 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581182-B1 | COMBINATION TREATING PROSTATE CANCER, PHARMACEUTICAL COMPOSITION AND TREATMENT METHOD | KANGPU BIOPHARMACEUTICALS LTD (CN) | 2021-09-29 | — | — | EP | disclosed |