Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25308853 | 0.77 | MEN1 (0.54) | MEN1KMT2AGRM5DDB1CRBN | |
| SCHEMBL31034869 | 0.77 | MEN1 (0.54) | MEN1KMT2AGRM5DDB1CRBN | |
| SCHEMBL21939251 | 0.77 | MEN1 (0.54) | MEN1KMT2AGRM5DDB1CRBN | |
| SCHEMBL31260453 | 0.76 | MEN1 (0.79) | MEN1KMT2AGRM5 | |
| SCHEMBL23997079 | 0.75 | MEN1 (0.51) | MEN1KMT2AGRM5DDB1CRBN | |
| SCHEMBL8227244 | 0.74 | MEN1 (0.62) | MEN1KMT2AGRM5DDB1CRBN | |
| SCHEMBL19887444 | 0.74 | AHR (0.41) | MEN1KMT2AAHRGRM5 | |
| SCHEMBL30038949 | 0.74 | MEN1 (0.50) | MEN1KMT2AGRM5AOC3 | |
| SCHEMBL172065 | 0.73 | GRM5 (0.56) | MEN1KMT2AGRM5AOC3 | |
| SCHEMBL31743068 | 0.73 | GRM5 (0.56) | MEN1KMT2AGRM5AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3572401-B1 | ASK1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |