Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25308853 | 1.00 | MEN1 (0.54) | MEN1KMT2AGRM5AOC3TYMS | |
| SCHEMBL29010819 | 0.83 | MEN1 (0.39) | MEN1KMT2ATYMSDDB1CRBN | |
| SCHEMBL31391626 | 0.83 | MEN1 (0.39) | MEN1KMT2ATYMSDDB1CRBN | |
| SCHEMBL31260453 | 0.79 | MEN1 (0.79) | MEN1KMT2AGRM5 | |
| SCHEMBL24869723 | 0.78 | MEN1 (0.77) | MEN1KMT2AGRM5AOC3 | |
| SCHEMBL30875685 | 0.78 | MEN1 (0.77) | MEN1KMT2AGRM5AOC3 | |
| SCHEMBL23865260 | 0.77 | MEN1 (0.54) | MEN1KMT2AGRM5AOC3DDB1 | |
| SCHEMBL21939251 | 0.77 | MEN1 (0.54) | MEN1KMT2AGRM5AOC3DDB1 | |
| SCHEMBL25947321 | 0.77 | MEN1 (0.50) | MEN1KMT2AGRM5AOC3DDB1 | |
| SCHEMBL18053937 | 0.75 | GRM5 (0.57) | MEN1KMT2AGRM5AOC3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118434729-A | Fused ring compounds as HPK1 inhibitors | 微境生物医药科技(上海)有限公司 | 2024-08-02 | — | — | CN | disclosed |