Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555051 | 1.00 | TRIM24 (0.46) | TRIM24TRIM33ATMPTGS2KMT2A | |
| SCHEMBL11879956 | 0.83 | TRIM24 (0.43) | TRIM24TRIM33ATMPTGS2KMT2A | |
| SCHEMBL11556583 | 0.81 | ATM (0.44) | TRIM24TRIM33ATMPTGS2SMN1; SMN2 | |
| SCHEMBL15331853 | 0.79 | BCL2 (0.40) | TRIM24TRIM33ATMPTGS2KMT2A | |
| SCHEMBL11876578 | 0.79 | BCL2 (0.40) | TRIM24TRIM33ATMPTGS2KMT2A | |
| SCHEMBL10505467 | 0.79 | TRIM24 (0.54) | TRIM24TRIM33ATMPTGS2KMT2A | |
| SCHEMBL11880901 | 0.78 | TRIM24 (0.42) | TRIM24TRIM33ATMPTGS2SMN1; SMN2 | |
| SCHEMBL11871896 | 0.78 | TRIM24 (0.39) | TRIM24TRIM33ATMPTGS2KMT2A | |
| SCHEMBL28276234 | 0.76 | ALDH1A1 (0.46) | PTGS2KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL11554293 | 0.75 | ATM (0.39) | TRIM24TRIM33ATMPTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3885437-A1 | DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF, AND METHOD TO SYNTHESIZE THE LIBRARY | Technische Universität Dortmund (DE) | 2021-09-29 | — | — | EP | disclosed |