Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 9/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 9/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23586136 | 0.74 | — | — | |
| SCHEMBL10123740 | 0.72 | SLC1A2 (0.54) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14037696 | 0.71 | SLC1A2 (0.52) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8389926 | 0.67 | FOLH1 (0.41) | GRIK1GRIK2 | |
| SCHEMBL2344654 | 0.67 | NAALAD2 (0.48) | — | |
| SCHEMBL12951360 | 0.67 | NAALAD2 (0.48) | — | |
| SCHEMBL18327109 | 0.67 | SLC1A2 (0.38) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL12891365 | 0.66 | ALDH1A1 (0.40) | — | |
| SCHEMBL17953984 | 0.66 | ALDH1A1 (0.40) | — | |
| SCHEMBL8971305 | 0.65 | FOLH1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287436-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN THE TREATMENT OF BCAT1-MEDIATED DISEASES | ERGON PHARMACEUTICALS LLC (US) | 2021-09-29 | — | — | EP | disclosed |