Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27375319 | 0.86 | CHRM4 (0.46) | GAATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL21384533 | 0.86 | GAA (0.41) | GAATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL21384366 | 0.86 | GAA (0.41) | GAATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL23368109 | 0.86 | CHRM4 (0.46) | GAATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL23859720 | 0.85 | LMNA (0.49) | TSHRALDH1A1POLBSMN1; SMN2ATM | |
| SCHEMBL20414854 | 0.82 | GAA (0.47) | GAATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL25839456 | 0.81 | USP2 (0.41) | TSHRALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21401618 | 0.77 | TSHR (0.44) | GAATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL29424723 | 0.77 | TSHR (0.44) | GAATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL23704607 | 0.75 | SMN1; SMN2 (0.55) | GAAHTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192654-A1 | PIPERAZINE AZASPIRO DERIVATIVES | PFIZER INC. | 2023-06-22 | — | — | US | disclosed |
| EP-3331528-B1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2021-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192654-A1 | PIPERAZINE AZASPIRO DERIVATIVES | CHRM1, CHRM2, CHRM5 | GAA 2320/4885TSHR 1403/4885ALDH1A1 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.