Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20744366 | 0.89 | NAMPT (0.48) | NAMPT | |
| SCHEMBL30711201 | 0.74 | EPHX2 (0.49) | CYP2C9EPHX2NAMPTKDM4E | |
| SCHEMBL20744365 | 0.74 | EPHX2 (0.47) | EPHX2 | |
| SCHEMBL19658657 | 0.73 | CYP2C9 (0.46) | CYP2C9EPHX2NAMPTKDM4E | |
| SCHEMBL19652152 | 0.72 | NAMPT (0.48) | CYP2C9EPHX2NAMPTKDM4E | |
| SCHEMBL20744358 | 0.71 | — | — | |
| SCHEMBL20744336 | 0.71 | — | — | |
| SCHEMBL20744178 | 0.71 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL20744363 | 0.70 | EPHX2 (0.50) | EPHX2 | |
| SCHEMBL30711274 | 0.69 | GPR119 (0.65) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668853-B1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2021-09-29 | — | — | EP | disclosed |