SCHEMBL23865614

SCHEMBL23865614

O=Cc1ccc(-c2ccc3c(c2)c2cc(Br)ccc2n3-c2ccc(C=O)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
KIF11 P52732 1/20 0.35
KDM4E B2RXH2 3/20 0.33
MAPKAPK2 P49137 1/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
JAK3 P52333 1/20 0.33
DRD1 P21728 2/20 0.33
PTGS2 P35354 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP2A6 P11509 1/20 0.33
PTGER4 P35408 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30194724 0.93 MAPKAPK2 (0.33) ALDH1A1KIF11KDM4EMAPKAPK2JAK3
SCHEMBL23358443 0.93 MAPKAPK2 (0.33) ALDH1A1KIF11KDM4EMAPKAPK2JAK3
SCHEMBL21689834 0.93 ALDH1A1 (0.39) ALDH1A1KDM4EJAK3DRD1CYP2A6
SCHEMBL30194685 0.93 ALDH1A1 (0.39) ALDH1A1KDM4EJAK3DRD1CYP2A6
SCHEMBL13158817 0.92 ALDH1A1 (0.40) ALDH1A1KDM4ETRIM24TRIM33JAK3
SCHEMBL29392880 0.92 ALDH1A1 (0.40) ALDH1A1KDM4ETRIM24TRIM33JAK3
SCHEMBL17515011 0.89 ALDH1A1 (0.42) ALDH1A1KDM4ETRIM24TRIM33JAK3
SCHEMBL22269676 0.85 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2MAPT
SCHEMBL22237642 0.85 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2MAPT
SCHEMBL30195085 0.85 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3366673-B1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2021-09-29 EP disclosed