Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18968300 | 1.00 | NCF1 (0.37) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18968080 | 1.00 | NCF1 (0.37) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18968298 | 1.00 | NCF1 (0.37) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18968114 | 1.00 | NCF1 (0.37) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14888163 | 0.83 | NCF1 (0.37) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1355855 | 0.83 | NCF1 (0.37) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1355857 | 0.83 | NCF1 (0.37) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13354978 | 0.83 | NCF1 (0.37) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14386288 | 0.83 | NCF1 (0.37) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL14311930 | 0.81 | NCF1 (0.35) | NCF1MRGPRX2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885342-A1 | BICYCLIC INHIBITORS OF PAD4 | Padlock Therapeutics, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |