SCHEMBL23865994

SCHEMBL23865994

Cc1ccc(S(=O)(=O)OCC(C)C2CCC3C4CCC5C[C@H](OS(=O)(=O)c6ccc(C)cc6)CCC5(C)C4CCC23C)cc1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ST6GAL1 P15907 3/20 0.59
GRIN1 Q05586 3/20 0.56
GRIN2B Q13224 3/20 0.56
VDR P11473 3/20 0.55
ABCC4 O15439 3/20 0.55
ABCC1 P33527 1/20 0.50
GPBAR1 Q8TDU6 1/20 0.49
USP2 O75604 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
NR1I2 O75469 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19253281 0.92 GRIN1 (0.64) ST6GAL1GRIN1GRIN2BVDRABCC4
SCHEMBL19253282 0.92 GRIN1 (0.64) ST6GAL1GRIN1GRIN2BVDRABCC4
SCHEMBL3135366 0.89 ST6GAL1 (0.63) ST6GAL1VDRABCC4
SCHEMBL23628425 0.89 ST6GAL1 (0.63) ST6GAL1VDRABCC4
SCHEMBL3135361 0.89 ST6GAL1 (0.63) ST6GAL1VDRABCC4
SCHEMBL11109512 0.89 ST6GAL1 (0.63) ST6GAL1VDRABCC4
SCHEMBL19705666 0.88 CA1 (0.52) ST6GAL1GRIN1GRIN2BGPBAR1USP2
SCHEMBL19253322 0.83 GRIN1 (0.67) ST6GAL1GRIN1GRIN2B
SCHEMBL19253320 0.83 GRIN1 (0.67) ST6GAL1GRIN1GRIN2B
SCHEMBL875405 0.81 CDC25A (0.62) ST6GAL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464315-B1 METHODS FOR THE PREPARATION OF DEOXYCHOLIC ACID, AND INTERMEDIATES USEFUL IN THE PREPARATION OF DEOXYCHOLIC ACID CRYSTAL PHARMA SAU (ES) 2021-09-29 EP disclosed