Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.64 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.57 |
| ▸ | VDR | P11473 | 3/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19253282 | 1.00 | GRIN1 (0.64) | GRIN1GRIN2BST6GAL1VDRABCC4 | |
| SCHEMBL23865994 | 0.92 | ST6GAL1 (0.59) | GRIN1GRIN2BST6GAL1VDRABCC4 | |
| SCHEMBL11109512 | 0.89 | ST6GAL1 (0.63) | ST6GAL1VDRABCC4 | |
| SCHEMBL23628425 | 0.89 | ST6GAL1 (0.63) | ST6GAL1VDRABCC4 | |
| SCHEMBL3135366 | 0.89 | ST6GAL1 (0.63) | ST6GAL1VDRABCC4 | |
| SCHEMBL3135361 | 0.89 | ST6GAL1 (0.63) | ST6GAL1VDRABCC4 | |
| SCHEMBL19733273 | 0.85 | GRIN1 (0.71) | GRIN1GRIN2BST6GAL1VDRABCC4 | |
| SCHEMBL19253320 | 0.83 | GRIN1 (0.67) | GRIN1GRIN2BST6GAL1 | |
| SCHEMBL19733274 | 0.83 | GRIN1 (0.84) | GRIN1GRIN2BST6GAL1VDRABCC4 | |
| SCHEMBL19253322 | 0.83 | GRIN1 (0.67) | GRIN1GRIN2BST6GAL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186267-B1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2019-10-02 | — | — | EP | disclosed |
| US-10017535-B2 | Amphiphilic compounds with neuroprotective properties | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2018-07-10 | — | — | US | disclosed |
| EP-3260462-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) | 2017-12-27 | — | — | EP | disclosed |
| US-20170240588-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240588-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | GAP43, GRIN2A, GRIN3A | GRIN1 14/4885GRIN2B 8/4885ST6GAL1 1060/4885 |
| US-10017535-B2 | Amphiphilic compounds with neuroprotective properties | GAP43, GRIN2A, GRIN3A | GRIN1 14/4885GRIN2B 8/4885ST6GAL1 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.