Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18967092 | 1.00 | MBTD1 (0.34) | MBTD1L3MBTL3NCF1HRH4GNAI3 | |
| SCHEMBL18967101 | 1.00 | MBTD1 (0.34) | MBTD1L3MBTL3NCF1HRH4GNAI3 | |
| SCHEMBL15338322 | 1.00 | MBTD1 (0.34) | MBTD1L3MBTL3NCF1HRH4GNAI3 | |
| SCHEMBL12560847 | 1.00 | MBTD1 (0.34) | MBTD1L3MBTL3NCF1HRH4GNAI3 | |
| Hydrochloric Acid SCHEMBL30938586 | 0.98 | MBTD1 (0.33) | MBTD1L3MBTL3NCF1HRH4GNAI3 | |
| Hydrochloric Acid SCHEMBL31430092 | 0.98 | MBTD1 (0.33) | MBTD1L3MBTL3NCF1HRH4GNAI3 | |
| SCHEMBL19343102 | 0.88 | MBTD1 (0.33) | MBTD1L3MBTL3HRH4 | |
| SCHEMBL10381139 | 0.88 | HRH4 (0.40) | MBTD1L3MBTL3NCF1HRH4 | |
| SCHEMBL12605050 | 0.87 | MBTD1 (0.34) | MBTD1L3MBTL3NCF1GNAI3GNAO1 | |
| SCHEMBL4406747 | 0.87 | MBTD1 (0.34) | MBTD1L3MBTL3NCF1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885342-A1 | BICYCLIC INHIBITORS OF PAD4 | Padlock Therapeutics, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |