Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12722376 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL1627514 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL12722501 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL1627237 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL21511186 | 0.89 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL16901911 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL3412240 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL3409477 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL15565349 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL15596784 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300878-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300878-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | TNNI3, TNNT2, FABP3 | SMN1; SMN2 2969/4885LMNA 3348/4885NPC1 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.