Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24838711 | 0.94 | L3MBTL1 (0.38) | KDM4EMAPTJAK2LMNAGAA | |
| SCHEMBL30178764 | 0.94 | L3MBTL1 (0.38) | KDM4EMAPTJAK2LMNAGAA | |
| SCHEMBL28348359 | 0.92 | NPC1 (0.41) | KDM4EMAPTJAK2LMNAGAA | |
| SCHEMBL28348109 | 0.92 | NPC1 (0.41) | KDM4EMAPTJAK2LMNAGAA | |
| SCHEMBL28348682 | 0.92 | NPC1 (0.41) | KDM4EMAPTJAK2LMNAGAA | |
| SCHEMBL28348108 | 0.92 | NPC1 (0.41) | KDM4EMAPTJAK2LMNAGAA | |
| SCHEMBL23630245 | 0.89 | KDM4E (0.40) | KDM4EMAPTJAK2LMNAGAA | |
| SCHEMBL30291428 | 0.89 | KDM4E (0.40) | KDM4EMAPTJAK2LMNAGAA | |
| SCHEMBL22005040 | 0.87 | KDM4E (0.44) | KDM4EMAPTJAK2LMNAGAA | |
| SCHEMBL2705419 | 0.87 | KDM4E (0.44) | KDM4EMAPTJAK2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148294-A1 | POLYMERIZATION CATALYST HAVING A TETRADENTATE LIGAND | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-05-11 | — | — | US | disclosed |
| US-20230148294-A1 | POLYMERIZATION CATALYST HAVING A TETRADENTATE LIGAND | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-05-11 | — | — | US | disclosed |
| WO-2021191724-A1 | POLYMERIZATION CATALYST HAVING A TETRADENTATE LIGAND | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2021-09-30 | — | — | WO | disclosed |
| CN-110563619-B | Aryl alkyl sulfone compound and reduction coupling method for constructing sulfone compound | 华东师范大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-110563619-A | Aryl alkyl sulfone compound and reduction coupling method for constructing sulfone compound | 华东师范大学 | 2019-12-13 | — | — | CN | disclosed |