Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30810207 | 0.85 | TACR1 (0.43) | MEN1KMT2ATACR1OPRD1OPRK1 | |
| SCHEMBL18163700 | 0.84 | MEN1 (0.47) | MEN1KMT2ATACR1OPRD1OPRK1 | |
| SCHEMBL30929236 | 0.81 | MEN1 (0.44) | MEN1KMT2AOPRD1OPRK1HTT | |
| SCHEMBL616090 | 0.79 | SCD5 (0.52) | MEN1KMT2ATACR1OPRD1OPRK1 | |
| SCHEMBL25447134 | 0.79 | MEN1 (0.49) | MEN1KMT2ATACR1OPRD1OPRK1 | |
| SCHEMBL30922395 | 0.79 | JAK2 (0.48) | TACR1OPRD1OPRK1JAK2JAK1 | |
| SCHEMBL28983636 | 0.79 | MEN1 (0.46) | MEN1KMT2ATACR1OPRD1OPRK1 | |
| SCHEMBL23582844 | 0.78 | MEN1 (0.46) | MEN1KMT2ATACR1OPRD1OPRK1 | |
| SCHEMBL23869608 | 0.78 | MEN1 (0.52) | MEN1KMT2ATACR1OPRD1OPRK1 | |
| SCHEMBL18154126 | 0.78 | TACR1 (0.44) | MEN1KMT2ATACR1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300906-A1 | PYRAZOLE DERIVATIVES AS H4 ANTAGONIST COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300906-A1 | PYRAZOLE DERIVATIVES AS H4 ANTAGONIST COMPOUNDS | HRH4, HRH3, HDAC3 | MEN1 2770/4885KMT2A 1080/4885TACR1 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.