SCHEMBL23870263

SCHEMBL23870263

Cc1c(F)ccc2ncoc12

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.36
ELANE P08246 1/20 0.33
ACLY P53396 1/20 0.32
MTNR1A P48039 3/20 0.31
MTNR1B P49286 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31597506 0.79 ACLY (0.33) ACLY
SCHEMBL8404404 0.79 ELANE (0.39) KCNA3ELANEMTNR1AMTNR1B
SCHEMBL30394936 0.76 DYRK1A (0.35) ACLY
SCHEMBL31040083 0.76 ACLY (0.32) ACLY
SCHEMBL28172478 0.76 KCNA3 (0.36) KCNA3ELANEMTNR1AMTNR1B
SCHEMBL12121768 0.76 ELANE (0.37) KCNA3ELANEMTNR1AMTNR1B
SCHEMBL23022302 0.76 KCNA3 (0.36) KCNA3ELANEMTNR1AMTNR1B
SCHEMBL29873503 0.75 DYRK1A (0.36) KCNA3ELANEMTNR1AMTNR1B
SCHEMBL3352320 0.71 ACLY (0.42) ELANEACLYMTNR1AMTNR1B
SCHEMBL12121764 0.71 KCNA3 (0.35) KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021195183-A1 COMPOSITIONS AND METHODS FOR INHIBITING PROTEIN EMBRYONIC ECTODERM DEVELOPMENT ACTIVITY AND TREATING DISEASE EXO THERAPEUTICS, INC. (US) 2021-09-30 WO disclosed