Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22890944 | 0.79 | NPC1 (0.67) | NPC1HRH3SIGMAR1 | |
| SCHEMBL27372831 | 0.77 | HRH3 (0.42) | NPC1HRH3SIGMAR1 | |
| SCHEMBL14654909 | 0.75 | NPC1 (0.60) | NPC1HRH3SIGMAR1 | |
| SCHEMBL27365596 | 0.74 | KDM4E (0.41) | HRH3 | |
| SCHEMBL20333607 | 0.73 | HRH3 (0.41) | NPC1HRH3SIGMAR1 | |
| SCHEMBL18713115 | 0.73 | NPC1 (0.67) | NPC1HRH3 | |
| SCHEMBL14500230 | 0.73 | KDM4E (0.51) | HRH3SIGMAR1 | |
| SCHEMBL27370585 | 0.71 | ALDH1A1 (0.41) | HRH3SIGMAR1 | |
| SCHEMBL22564720 | 0.70 | HRH3 (0.46) | NPC1HRH3 | |
| SCHEMBL20234240 | 0.70 | HRH3 (0.41) | NPC1HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195183-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PROTEIN EMBRYONIC ECTODERM DEVELOPMENT ACTIVITY AND TREATING DISEASE | EXO THERAPEUTICS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |