SCHEMBL238723

SCHEMBL238723

C=CC(=O)OCC[SiH](OCCC)OCCC

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.56
HPGD P15428 1/20 0.56
ALDH1A1 P00352 5/20 0.47
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
CYP3A4 P08684 2/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 4/20 0.44
HCAR2 Q8TDS4 4/20 0.39
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5698950 0.90 TSHR (0.68) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL107694 0.90 TSHR (0.62) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1285195 0.88 TSHR (0.61) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL238023 0.87 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16286805 0.87 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL108962 0.84 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL140103 0.81 TSHR (0.71) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL17536049 0.81 HCAR2 (0.46) TSHRHPGDHCAR2ATM
SCHEMBL14982 0.80
SCHEMBL30074662 0.80 TSHR (0.75) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053528-B2 Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-11-08 US claimed
EP-2164902-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM Georgia-Pacific Chemicals LLC (US) 2010-03-24 EP claimed
US-20090124151-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-05-14 US claimed
WO-2008150647-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS, LLC (US) 2008-12-11 WO claimed
US-20240279441-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-08-22 US disclosed
US-11530318-B2 Rubber composition and pneumatic tire BRIDGESTONE CORPORATION (JP) 2022-12-20 US disclosed
WO-2022254751-A1 RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2022-12-08 WO disclosed
EP-3725836-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2022-08-24 EP disclosed
CN-111465645-A Rubber composition and pneumatic tire 株式会社普利司通 2020-07-28 CN disclosed
CN-108602987-B Rubber composition and tire 株式会社普利司通 2020-07-21 CN disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-9745406-B2 Curable composition CEMEDINE CO., LTD. (JP) 2017-08-29 US disclosed
EP-2412756-B1 CURABLE COMPOSITION CEMEDINE CO LTD (JP) 2016-12-21 EP disclosed
EP-2412756-A1 CURABLE COMPOSITION CEMEDINE CO., LTD. (JP) 2012-02-01 EP disclosed
US-20120004371-A1 CURABLE COMPOSITION CEMEDINE CO., LTD. (JP) 2012-01-05 US disclosed
US-8053528-B2 Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-11-08 US disclosed
EP-2164902-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM Georgia-Pacific Chemicals LLC (US) 2010-03-24 EP disclosed
US-20090124151-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-05-14 US disclosed
WO-2008150647-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS, LLC (US) 2008-12-11 WO disclosed