Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236552 | 0.89 | TSHR (0.65) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL107385 | 0.85 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL238723 | 0.84 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL107694 | 0.81 | TSHR (0.62) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL675802 | 0.80 | HCAR2 (0.43) | TSHRHPGDHCAR2ATM | |
| SCHEMBL1285195 | 0.80 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL16286805 | 0.78 | TSHR (0.59) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL30074662 | 0.78 | TSHR (0.75) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14982 | 0.78 | — | — | |
| SCHEMBL2415583 | 0.76 | ALDH1A1 (0.46) | TSHRALDH1A1HSD17B10HCAR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4035649-B1 | DENTAL ADHESIVE COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-07-26 | — | — | EP | claimed |
| EP-4035649-A1 | DENTAL ADHESIVE COMPOSITION | 3M Innovative Properties Company (US) | 2022-08-03 | — | — | EP | claimed |
| US-20260028440-A1 | Curable Composition for Producing Transparent Orthodontic Attachments | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2026-01-29 | — | — | US | disclosed |
| EP-4558086-A1 | CURABLE COMPOSITION FOR PRODUCING TRANSPARENT ORTHODONTIC ATTACHMENTS | Solventum Intellectual Properties Company (US) | 2025-05-28 | — | — | EP | disclosed |
| US-12240868-B2 | Organic silicon compound and production method therefor | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-03-04 | — | — | US | disclosed |
| US-20240358603-A1 | One-Part Dental Adhesive Composition for Fixing Dental Composite Materials | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-10-31 | — | — | US | disclosed |
| US-12070514-B2 | One-part dental adhesive composition for fixing dental composite materials | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-08-27 | — | — | US | disclosed |
| US-20240279441-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2024-08-22 | — | — | US | disclosed |
| US-20240279459-A1 | Curable Composition and Cured Product | SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) | 2024-08-22 | — | — | US | disclosed |
| EP-4353755-A1 | CURABLE COMPOSITION AND CURED PRODUCT | Soken Chemical & Engineering Co., Ltd. (JP) | 2024-04-17 | — | — | EP | disclosed |
| CN-117529524-A | Curable composition and cured product | 综研化学株式会社 | 2024-02-06 | — | — | CN | disclosed |
| EP-1711537-A1 | CURABLE COMPOSITION CONTAINING SURFACE-MODIFIED PARTICLES | Consortium für elektrochemische Industrie GmbH (DE) | 2006-10-18 | — | — | EP | disclosed |
| EP-1473296-B1 | Organofunctional surface modified metal oxides | WACKER CHEMIE AG (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005092932-A1 | CURABLE COMPOSITION CONTAINING SURFACE-MODIFIED PARTICLES | Consortium für elektrochemische Industrie GmbH (DE) | 2005-10-06 | — | — | WO | disclosed |
| EP-1473296-A1 | Organofunctional surface modified metal oxides | Wacker-Chemie GmbH (DE) | 2004-11-03 | — | — | EP | disclosed |
| US-6653404-B2 | Melt processability; dimensional stability | JSR CORPORATION (JP) | 2003-11-25 | — | — | US | disclosed |
| US-20010053813-A1 | Rubber compositions | JSR CORPORATION (JP) | 2001-12-20 | — | — | US | disclosed |
| EP-0486279-B2 | Process for removing acidic impurities from alkoxysilanes | SHINETSU CHEMICAL CO (JP) | 1999-12-01 | — | — | EP | disclosed |
| US-5247117-A | Neutralization with sterically hindered alcohols or amines, distillation | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0486279-A1 | Process for removing acidic impurities from alkoxysilanes | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240358603-A1 | One-Part Dental Adhesive Composition for Fixing Dental Composite Materials | CDH1, F12, ACTN1 | TSHR 4762/4885HPGD 336/4885ALDH1A1 78/4885 |
| US-20260028440-A1 | Curable Composition for Producing Transparent Orthodontic Attachments | SMCHD1, SMC2, SMC1A | TSHR 705/4885HPGD 4304/4885ALDH1A1 1413/4885 |
| US-12240868-B2 | Organic silicon compound and production method therefor | OR51E2, MSL1, SOS1 | TSHR 4456/4885HPGD 4522/4885ALDH1A1 2353/4885 |
| US-12070514-B2 | One-part dental adhesive composition for fixing dental composite materials | CDH1, F12, ACTN1 | TSHR 4762/4885HPGD 336/4885ALDH1A1 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.