⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24466973 | 0.84 | — | — | |
| SCHEMBL27869430 | 0.82 | — | — | |
| SCHEMBL13826264 | 0.82 | — | — | |
| SCHEMBL12517534 | 0.80 | — | — | |
| SCHEMBL10256261 | 0.80 | — | — | |
| SCHEMBL341738 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL3764161 | 0.78 | MAPT (0.47) | — | |
| SCHEMBL15650950 | 0.77 | L3MBTL1 (0.44) | — | |
| SCHEMBL15986772 | 0.77 | MAPT (0.42) | — | |
| SCHEMBL16943123 | 0.77 | MAPT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021194878-A1 | SELECTIVE MODULATORS OF MUTANT LRRK2 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |