SCHEMBL23875464 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	ABCB1	P08183	1/20	0.34

▸	AR	P10275	1/20	0.33

▸	KDM4E	B2RXH2	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	PDE5A	O76074	1/20	0.32

▸	PDE4A	P27815	1/20	0.32

▸	PDE1A	P54750	1/20	0.32

▸	PDE1B	Q01064	1/20	0.32

▸	PDE4B	Q07343	1/20	0.32

▸	PDE4C	Q08493	1/20	0.32

▸	PDE4D	Q08499	1/20	0.32

▸	PDE1C	Q14123	1/20	0.32

▸	GUCY1A1	Q02108	1/20	0.30

▸	GUCY1B1	Q02153	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23875659	0.90	AR (0.34)	ARKDM4EALDH1A1PDE5APDE4A
SCHEMBL19922786	0.82	HDAC6 (0.35)	ARKDM4EALDH1A1PDE5APDE4A
SCHEMBL19922661	0.81	HDAC6 (0.34)	ARKDM4EALDH1A1PDE5APDE4A
SCHEMBL19922662	0.81	HDAC6 (0.34)	ARKDM4EALDH1A1PDE5APDE4A
SCHEMBL19922956	0.81	HDAC6 (0.36)	ARKDM4EALDH1A1PDE5APDE4A
SCHEMBL19922658	0.79	HDAC6 (0.32)	ARKDM4EALDH1A1PDE5APDE4A
SCHEMBL19922778	0.78	AR (0.34)	ARKDM4EALDH1A1PDE5APDE4A
Zagociguat SCHEMBL19922804	0.78	AR (0.34)	ARKDM4EALDH1A1PDE5APDE4A
SCHEMBL19922665	0.78	AR (0.34)	ARKDM4EALDH1A1PDE5APDE4A
SCHEMBL19922744	0.78	PDE5A (0.36)	ARKDM4EALDH1A1PDE5APDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021195403-A1	DEUTERATED SGC STIMULATORS	CYCLERION THERAPEUTICS, INC. (US)	2021-09-30	—	—	WO	disclosed