SCHEMBL2387562

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1700329	0.92	WNK1 (0.54)	WNK1MAPTPOLBTDP1HCAR3
	SCHEMBL1700327	0.92	WNK1 (0.54)	WNK1MAPTPOLBTDP1HCAR3
	SCHEMBL1699924	0.89	WNK1 (0.51)	WNK1MAPTPOLBTDP1HCAR3
	SCHEMBL1542018	0.88	WNK1 (0.70)	WNK1MAPTPOLBTDP1HCAR3
	SCHEMBL30921518	0.88	WNK1 (0.50)	WNK1MAPTPOLBTDP1HCAR3
	SCHEMBL1699910	0.88	WNK1 (0.50)	WNK1MAPTPOLBTDP1HCAR3
	SCHEMBL1700110	0.88	WNK1 (0.50)	WNK1MAPTPOLBTDP1HCAR3
	SCHEMBL1699907	0.88	WNK1 (0.50)	WNK1MAPTPOLBTDP1HCAR3
	SCHEMBL16037632	0.87	MAPT (0.54)	WNK1MAPTPOLBTDP1GAA
	SCHEMBL24775192	0.87	WNK1 (0.49)	WNK1MAPTPOLBTDP1HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.