Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076246 | 0.87 | MEN1 (0.38) | MEN1KMT2AKDM4E | |
| SCHEMBL22848852 | 0.87 | MEN1 (0.38) | MEN1KMT2AKDM4E | |
| SCHEMBL23695892 | 0.87 | MEN1 (0.38) | MEN1KMT2AKDM4E | |
| SCHEMBL5933549 | 0.85 | HSD17B10 (0.33) | MEN1KMT2A | |
| SCHEMBL9024417 | 0.83 | — | — | |
| SCHEMBL22848580 | 0.82 | SCN1A (0.36) | MEN1KMT2A | |
| SCHEMBL20127150 | 0.82 | TSHR (0.36) | MEN1KMT2AKDM4ERECQL | |
| Ammonia Solution, Strong SCHEMBL29051935 | 0.81 | KDM4E (0.32) | MEN1KMT2AKDM4E | |
| SCHEMBL21106801 | 0.79 | MEN1 (0.35) | MEN1KMT2AKDM4ERECQL | |
| SCHEMBL21480809 | 0.79 | SCN1A (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021194878-A1 | SELECTIVE MODULATORS OF MUTANT LRRK2 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |