Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.46 |
| ▸ | FAP | Q12884 | 10/20 | 0.46 |
| ▸ | DPP4 | P27487 | 8/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25893586 | 0.84 | PREP (0.50) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL23876235 | 0.84 | PREP (0.56) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL25896700 | 0.83 | PREP (0.49) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL23876225 | 0.80 | PREP (0.64) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL23876489 | 0.79 | DPP4 (0.55) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL23876224 | 0.78 | PREP (0.56) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL25896825 | 0.77 | FAP (0.43) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL25892342 | 0.77 | PREP (0.56) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL23876867 | 0.77 | PREP (0.64) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL23876545 | 0.76 | FAP (0.62) | PREPFAPDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195198-A1 | FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE (US) | 2021-09-30 | — | — | WO | disclosed |