Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 15/20 | 0.59 |
| ▸ | FAP | Q12884 | 14/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.57 |
| ▸ | DPP4 | P27487 | 8/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890443 | 0.81 | PREP (0.63) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25890297 | 0.81 | PREP (0.77) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25890370 | 0.79 | FAP (0.74) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25890341 | 0.77 | PREP (0.79) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25896282 | 0.76 | PREP (0.60) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL27262345 | 0.75 | PREP (0.50) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL29359250 | 0.73 | PREP (1.00) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25892185 | 0.73 | PREP (0.52) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL31758426 | 0.72 | FAP (0.61) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25896160 | 0.72 | PREP (0.55) | PREPFAPDPP8DPP9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195198-A1 | FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE (US) | 2021-09-30 | — | — | WO | disclosed |