Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 18/20 | 0.53 |
| ▸ | DPP4 | P27487 | 18/20 | 0.53 |
| ▸ | PREP | P48147 | 9/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12372017 | 0.87 | FAP (0.69) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL13263677 | 0.87 | FAP (0.69) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL14012476 | 0.79 | FAP (0.81) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL15430071 | 0.76 | DPP4 (0.81) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL28215261 | 0.73 | POLB (0.39) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL22224360 | 0.73 | POLB (0.39) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL13245892 | 0.73 | HPGD (0.47) | DPP4 | |
| SCHEMBL13674784 | 0.73 | HPGD (0.47) | DPP4 | |
| SCHEMBL14301360 | 0.73 | HPGD (0.47) | DPP4 | |
| SCHEMBL14926821 | 0.73 | POLB (0.40) | FAPDPP4PREPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195198-A1 | FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE (US) | 2021-09-30 | — | — | WO | disclosed |