SCHEMBL23877006

CSC(=O)OCc1ccc(NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](CS(=O)(=O)O)NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	FAP	Q12884	5/20	0.44

▸	MAP1LC3B	Q9GZQ8	2/20	0.36

▸	NPY5R	Q15761	4/20	0.36

▸	NPY1R	P25929	3/20	0.36

▸	NPY4R	P50391	3/20	0.36

▸	NPY2R	P49146	1/20	0.36

▸	SIRT2	Q8IXJ6	7/20	0.35

▸	SIRT1	Q96EB6	5/20	0.35

▸	SIRT3	Q9NTG7	3/20	0.35

▸	FURIN	P09958	2/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17722946	0.94	FAP (0.45)	FAPMAP1LC3BNPY5RNPY1RNPY4R
SCHEMBL22643670	0.94	FAP (0.45)	FAPMAP1LC3BNPY5RNPY1RNPY4R
SCHEMBL19704788	0.94	FAP (0.45)	FAPMAP1LC3BNPY5RNPY1RNPY4R
SCHEMBL22314405	0.94	FAP (0.45)	FAPMAP1LC3BNPY5RNPY1RNPY4R
SCHEMBL20935053	0.94	FAP (0.45)	FAPMAP1LC3BNPY5RNPY1RNPY4R
SCHEMBL17815311	0.94	FAP (0.45)	FAPMAP1LC3BNPY5RNPY1RNPY4R
SCHEMBL21861811	0.94	FAP (0.45)	FAPMAP1LC3BNPY5RNPY1RNPY4R
SCHEMBL21998545	0.94	FAP (0.45)	FAPMAP1LC3BNPY5RNPY1RNPY4R
SCHEMBL21912925	0.94	FAP (0.45)	FAPMAP1LC3BNPY5RNPY1RNPY4R
SCHEMBL22697428	0.92	FAP (0.47)	FAPMAP1LC3BNPY5RNPY1RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021195513-A1	BISPECIFIC COMBINATION THERAPY FOR TREATING PROLIFERATIVE DISEASES AND AUTOIMMUNE DISORDERS	NOVARTIS AG (CH)	2021-09-30	—	—	WO	disclosed