SCHEMBL238787

SCHEMBL238787

COCc1ccc2ccccc2n1

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYSLTR1 Q9Y271 8/20 0.62
CYSLTR2 Q9NS75 2/20 0.62
PDE10A Q9Y233 4/20 0.53
GPBAR1 Q8TDU6 8/20 0.53
CYP1A2 P05177 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30824506 1.00 CYSLTR1 (0.62) CYSLTR1CYSLTR2PDE10AGPBAR1CYP1A2
SCHEMBL2353460 0.83 CYSLTR1 (0.67) CYSLTR1CYSLTR2PDE10AGPBAR1
SCHEMBL18546229 0.81 FFAR1 (0.48) CYSLTR1CYSLTR2PDE10AGPBAR1
SCHEMBL4268808 0.81 CYSLTR1 (0.59) CYSLTR1CYSLTR2PDE10AGPBAR1CYP1A2
SCHEMBL1262903 0.80 CYSLTR1 (0.62) CYSLTR1CYSLTR2PDE10AGPBAR1CYP1A2
SCHEMBL1715309 0.80 CYSLTR1 (0.62) CYSLTR1CYSLTR2PDE10AGPBAR1
SCHEMBL13314537 0.79 CYSLTR1 (0.57) CYSLTR1CYSLTR2PDE10AGPBAR1CYP1A2
SCHEMBL12530278 0.79 CYSLTR1 (0.57) CYSLTR1CYSLTR2PDE10AGPBAR1CYP1A2
SCHEMBL10547475 0.79 CYSLTR1 (0.76) CYSLTR1CYSLTR2PDE10AGPBAR1
SCHEMBL7509236 0.78 CYSLTR1 (0.62) CYSLTR1CYSLTR2PDE10AGPBAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-01-25 US disclosed
WO-2024006881-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2024-01-04 WO disclosed
WO-2023205778-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-10-26 WO disclosed
EP-4230620-A1 SUBSTITUTED N-AMINO-N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS Bayer Aktiengesellschaft (DE) 2023-08-23 EP disclosed
EP-4230621-A1 SUBSTITUTED N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS Bayer AG (DE) 2023-08-23 EP disclosed
WO-2021013800-A1 SUBSTITUTED N-PHENYL-N-AMINOUARCILS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-01-28 WO disclosed
WO-2021013799-A1 SUBSTITUTED N-PHENYL URACILS, SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-01-28 WO disclosed
CN-106232572-B The manufacturing method of nitro compound 住友化学株式会社 2018-11-13 CN disclosed
CN-105399599-B A kind of method for preparing hexachlorobutadiene 浙江工业大学 2018-05-29 CN disclosed
CN-106164041-B The manufacture method of nitro compound 住友化学株式会社 2018-05-04 CN disclosed
WO-2004089416-A2 COMBINATION OF AN 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND AN ANTIHYPERTENSIVE AGENT NOVO NORDISK A/S (DK) 2004-10-21 WO disclosed
WO-2004089380-A2 PHARMACEUTICAL USE OF FUSED 1,2,4-TRIAZOLES NOVO NORDISK A/S (DK) 2004-10-21 WO disclosed
WO-2004089470-A2 NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF NOVO NORDISK A/S (DK) 2004-10-21 WO disclosed
WO-2004089471-A2 NEW PYRAZOLO[1,5-a] PYRIMIDINES DERIVATIVES AND PHARMACEUTICAL USE THEREOF NOVO NORDISK A/S (DK) 2004-10-21 WO disclosed
WO-2004089896-A1 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ACTIVE COMPOUNDS NOVO NORDISK A/S (DK) 2004-10-21 WO disclosed
WO-2004089415-A2 COMBINATIONS OF AN 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND A GLUCOCORTICOID RECEPTOR AGONIST NOVO NORDISK A/S (DK) 2004-10-21 WO disclosed
WO-2004002960-A1 SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS SCHERING AKTIENGESELLSCHAFT (DE) 2004-01-08 WO disclosed
US-4252945-A 4(1H)-QUINOLONES REACTED WITH HYDRAZINE TO FORM 5-(2-AMINOPHENYL)PYRAZOLES WHICH ARE CYCLIZED WITH PHOSGENE, THIOPHOSGENE OR ETHYL CHLOROFORMATE E. R. SQUIBB & SONS, INC. (US) 1981-02-24 US disclosed
US-4166862-A WEIGHT-GAIN PROMOTERS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1979-09-04 US disclosed
US-4163746-A ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1979-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES PFAS, DDT, NOTUM CYSLTR1 3539/4885CYSLTR2 3784/4885PDE10A 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.