SCHEMBL2387967

SCHEMBL2387967

FC(Cl)(C(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225726 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL2813250 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL2810230 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL2815348 0.74 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL1900145 0.72 ALDH1A1 (0.30) ALDH1A1HSD17B10
SCHEMBL10965452 0.70
SCHEMBL28941 0.70
SCHEMBL339702 0.70
SCHEMBL1993224 0.69
SCHEMBL1995255 0.69 ALDH1A1 (0.33) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2374782-B1 PROCESSES FOR PRODUCING 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE AND 2,3,3,3-TETRAFLUOROPROPENE ASAHI GLASS CO LTD (JP) 2014-09-17 EP disclosed
US-8395001-B2 Processes for producing 2-chloro-1,1,1,2-tetrafluoropropane and 2,3,3,3-tetrafluoropropene ASAHI GLASS COMPANY, LIMITED (JP) 2013-03-12 US disclosed
EP-2374782-A1 PROCESSES FOR PRODUCING 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE AND 2,3,3,3-TETRAFLUOROPROPENE Asahi Glass Company Limited (JP) 2011-10-12 EP disclosed
US-20110237846-A1 PROCESSES FOR PRODUCING 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE AND 2,3,3,3-TETRAFLUOROPROPENE ASAHI GLASS COMPANY, LIMITED (JP) 2011-09-29 US disclosed
US-5264639-A Fluorination of chlorine containing 2,2-halogenopropane with hydrogen fluoride ASAHI GLASS COMPANY LTD. (JP) 1993-11-23 US disclosed
EP-0407622-A1 PROCESS FOR PRODUCING A 2,2-DIFLUOROPROPANE. ASAHI GLASS CO LTD (JP) 1991-01-16 EP disclosed
WO-1990008754-A2 PROCESS FOR PRODUCING A 2,2-DIFLUOROPROPANE ASAHI GLASS COMPANY LTD. (JP) 1990-08-09 WO disclosed