Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21649536 | 1.00 | PIK3CD (0.45) | PIK3CDHSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL24344800 | 1.00 | PIK3CD (0.45) | PIK3CDHSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15343542 | 0.81 | HSD17B10 (0.39) | PIK3CDHSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL23469838 | 0.81 | HSD17B10 (0.39) | PIK3CDHSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL771983 | 0.79 | HSD17B10 (0.39) | PIK3CDHSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21649512 | 0.79 | HSD17B10 (0.39) | PIK3CDHSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL23432880 | 0.78 | HSD17B10 (0.38) | HSD17B10SMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13036147 | 0.77 | HSD17B10 (0.42) | PIK3CDHSD17B10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL23717362 | 0.77 | RIPK1 (0.42) | PIK3CDHSD17B10KDM4EACKR3 | |
| SCHEMBL12989181 | 0.77 | HSD17B10 (0.38) | PIK3CDHSD17B10SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136320-B2 | Fused ring derivative used as FGFR4 inhibitor | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136320-B2 | Fused ring derivative used as FGFR4 inhibitor | FGFR4, FGFR1, FGFR3 | PIK3CD 765/4885HSD17B10 493/4885SMN1; SMN2 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.