SCHEMBL2388015

SCHEMBL2388015

NC(O)C(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.58
CES2 O00748 3/20 0.58
LMNA P02545 2/20 0.58
TDP1 Q9NUW8 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MAPT P10636 3/20 0.50
CYP3A4 P08684 3/20 0.50
TSHR P16473 2/20 0.50
POLB P06746 1/20 0.50
PARP1 P09874 1/20 0.50
CYP2C19 P33261 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALKBH5 Q6P6C2 1/20 0.48
MDM2 Q00987 1/20 0.48
ALDH1A1 P00352 3/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3751620 0.82 TDP1 (0.56) CES1CES2LMNATDP1L3MBTL1
SCHEMBL9450434 0.82 TDP1 (0.56) CES1CES2LMNATDP1L3MBTL1
SCHEMBL27548850 0.80 TDP1 (0.54) CES1CES2LMNATDP1L3MBTL1
SCHEMBL30309190 0.79 LMNA (0.52) CES1CES2LMNATDP1L3MBTL1
SCHEMBL157066 0.79 CES1 (0.62) CES1CES2LMNATDP1L3MBTL1
SCHEMBL1549080 0.79 CES1 (0.62) CES1CES2LMNATDP1L3MBTL1
Dealkylated Diethylpropion SCHEMBL25176894 0.78 TDP1 (0.52) CES1CES2LMNATDP1L3MBTL1
SCHEMBL9618881 0.78 TDP1 (0.52) CES1CES2LMNATDP1L3MBTL1
SCHEMBL932126 0.78 TDP1 (0.52) CES1CES2LMNATDP1L3MBTL1
Dealkylated Diethylpropion SCHEMBL2236790 0.78 TDP1 (0.52) CES1CES2LMNATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110520796-A Polymerizable composition, polymerizable composition, black matrix\" photosensitive composite and black column spacer photosensitive composite ADEKA CORP 2019-11-29 CN claimed
CN-106831457-B A kind of preparation method of 3- amino -2- hydroxy acetophenone 上海微巨实业有限公司 2019-01-08 CN claimed
CN-101450943-B Method for synthesizing drug pranlukast from tetrahydrofuran path UNIV HEBEI SCIENCE & TECH 2012-11-07 CN claimed
CN-101450943-A Method for synthesizing drug pranlukast from tetrahydrofuran path UNIV HEBEI SCIENCE & TECH (CN) 2009-06-10 CN claimed
EP-0401166-B1 Nitrogen-containing titanocenes and their use CIBA GEIGY AG (CH) 1995-02-22 EP claimed
EP-0039903-B1 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF SUNTORY KABUSHIKI KAISHA (JP) 1986-04-09 EP claimed
CN-110423204-A A kind of preparation method of Pranlukast intermediate KUNSHAN RIKITA PHARMACEUTICAL CO LTD 2019-11-08 CN disclosed
CN-102791365-B Polyamide membrane with a coating comprising polyalkylene oxide and acetophenone compounds DOW GLOBAL TECHNOLOGIES LLC 2014-12-24 CN disclosed
US-8721942-B2 Composite membrane including coating of polyalkylene oxide and acetophenone compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2014-05-13 US disclosed
CN-102791365-A Polyamide membrane with a coating comprising polyalkylene oxide and acetophenone compounds DOW GLOBAL TECHNOLOGIES LLC 2012-11-21 CN disclosed
CN-101450943-B Method for synthesizing drug pranlukast from tetrahydrofuran path UNIV HEBEI SCIENCE & TECH 2012-11-07 CN disclosed
WO-2011112351-A1 POLYAMIDE MEMBRANE WITH A COATING COMPRISING POLYALKYLENE OXIDE AND ACETOPHENONE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-09-15 WO disclosed
US-20110220569-A1 COMPOSITE MEMBRANE INCLUDING COATING OF POLYALKYLENE OXIDE AND ACETOPHENONE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC 2011-09-15 US disclosed
US-5393860-A Functional monomers for high performance polymers HOECHST CELANESE CORPORATION (US) 1995-02-28 US disclosed
US-5349090-A Process for preparing arylketoamines HOECHST CELANESE CORPORATION (US) 1994-09-20 US disclosed
US-4963470-A PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1990-10-16 US disclosed
US-4327091-A ANTIINFLAMMATORY AGENTS CIBA-GEIGY CORPORATION (US) 1982-04-27 US disclosed
EP-0003360-B1 AZATHIANAPHTHALENE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR UTILISATION CIBA-GEIGY AG (CH) 1981-12-30 EP disclosed
US-4213980-A ANTIINFLAMMATORY AGENTS CIBA-GEIGY CORPORATION (US) 1980-07-22 US disclosed
EP-0003360-A1 Azathianaphthalene derivatives, process for their preparation, pharmaceutical preparations containing them and their utilisation CIBA-GEIGY AG (CH) 1979-08-08 EP disclosed