SCHEMBL2388503

SCHEMBL2388503

CCCc1c(C)c(C)c(C)c2sc3c(C)cccc3c12

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
CFTR P13569 5/20 0.35
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
HPGD P15428 3/20 0.34
GAA P10253 1/20 0.34
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
HSD17B10 Q99714 2/20 0.31
ALKBH5 Q6P6C2 1/20 0.30
FTO Q9C0B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2388062 0.91 TSHR (0.40) TSHRCFTRRAB9AALDH1A1KDM4E
SCHEMBL2387412 0.87 CYP2A6 (0.34) TSHRALDH1A1CYP1A2CYP2A6
SCHEMBL2387356 0.84 CYP2A6 (0.34) TSHRALDH1A1CYP1A2CYP2A6
SCHEMBL2386820 0.83 HSD17B3 (0.33) TSHRHSD17B10
SCHEMBL2384193 0.81 KDM4E (0.38) TSHRRAB9AALDH1A1KDM4EHPGD
SCHEMBL2385846 0.79 CYP2A6 (0.42) TSHRALDH1A1KDM4ECYP1A2CYP2A6
SCHEMBL2387322 0.74 KDM4E (0.33) TSHRKDM4EHSD17B10
SCHEMBL2388192 0.73 L3MBTL1 (0.40) TSHRRAB9AALDH1A1KDM4EHPGD
SCHEMBL28577444 0.72 HTT (0.34) TSHRALDH1A1GAA
SCHEMBL29364650 0.71 CYP1A2 (0.55) TSHRALDH1A1HPGDCYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105992808-B Use of magnetic nanoparticles for depleting aromatic compounds in oil 综合E&P丹麦股份有限公司 2018-10-19 CN disclosed
US-9969943-B2 Use of magnetic nanoparticles for depletion of aromatic compounds in oil MAERSK OLIE OG GAS A/S (DK) 2018-05-15 US disclosed
US-20160272898-A1 USE OF MAGNETIC NANOPARTICLES FOR DEPLETION OF AROMATIC COMPOUNDS IN OIL TOTAL E&P DANMARK A/S (DK) 2016-09-22 US disclosed
WO-2015044449-A1 USE OF MAGNETIC NANOPARTICLES FOR DEPLETION OF AROMATIC COMPOUNDS IN OIL MÆRSK OLIE OG GAS A/S (DK) 2015-04-02 WO disclosed
US-8021540-B2 Method of desulfurizing hydrocarbon oil JAPAN ENERGY CORPORATION (JP) 2011-09-20 US disclosed
US-20100227229-A1 SOLID ACID, METHOD FOR PREPARING THE SOLID ACID, AND METHOD FOR DESULFURIZING HYDROCARBON OIL USING THE SOILD ACID AS DESULFURIZING AGENT JAPAN ENERGY CORPORATION (JP) 2010-09-09 US disclosed
EP-2202204-A1 SOLID ACID, PROCESS FOR PRODUCING THE SOLID ACID, METHOD FOR DESULFURIZING HYDROCARBON OIL USING SOLID ACID AS DESULFURIZING AGENT Japan Energy Corporation (JP) 2010-06-30 EP disclosed
US-20100155303-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2010-06-24 US disclosed
US-20090000990-A1 Method of Desulfurizing Hydrocarbon Oil JAPAN ENERGY CORPORATION (JP) 2009-01-01 US disclosed
EP-1923451-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2008-05-21 EP disclosed
CN-1914298-A Method of desulfurizing hydrocarbon oil JAPAN ENERGY CORP (JP) 2007-02-14 CN disclosed
EP-1715025-A1 METHOD OF DESULFURIZING HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2006-10-25 EP disclosed