Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 6/20 | 0.43 | |
| ▸ | CFD | P00746 | 10/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928169 | 0.86 | CFD (0.43) | CFDHPGD | |
| SCHEMBL23885416 | 0.86 | CFD (0.43) | CFDHPGD | |
| SCHEMBL25266408 | 0.85 | USP30 (0.42) | PDFCFDKIF18AGRM5 | |
| SCHEMBL25203445 | 0.85 | USP30 (0.42) | PDFCFDKIF18AGRM5 | |
| SCHEMBL18555121 | 0.84 | CFD (0.42) | CFDCYP2C9 | |
| SCHEMBL18554860 | 0.82 | CFD (0.42) | CFDCYP2C9 | |
| SCHEMBL18554306 | 0.81 | CFD (0.47) | CFDHPGDCYP2C9 | |
| SCHEMBL18554304 | 0.81 | CFD (0.47) | CFDHPGDCYP2C9 | |
| SCHEMBL18554933 | 0.79 | CFD (0.53) | CFDHPGDCYP2C9GRM5 | |
| SCHEMBL18554936 | 0.79 | CFD (0.53) | CFDHPGDCYP2C9GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125914-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021202977-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-10-07 | — | — | WO | disclosed |