Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 17/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20229850 | 0.89 | HRH3 (0.38) | ROCK2 | |
| SCHEMBL17454418 | 0.89 | ROCK2 (0.41) | ROCK2CACNA1H | |
| SCHEMBL17452669 | 0.85 | ROCK2 (0.41) | ROCK2CACNA1H | |
| SCHEMBL17437924 | 0.85 | ROCK2 (0.42) | ROCK2CACNA1H | |
| SCHEMBL23889073 | 0.85 | PARP10 (0.38) | ROCK2 | |
| SCHEMBL21947212 | 0.83 | ROCK2 (0.39) | ROCK2CACNA1H | |
| SCHEMBL20229842 | 0.82 | ROCK2 (0.38) | ROCK2 | |
| SCHEMBL21947217 | 0.81 | CYP1A2 (0.39) | ROCK2 | |
| SCHEMBL19902548 | 0.81 | PDE4D (0.39) | ROCK2 | |
| SCHEMBL19997307 | 0.78 | MEN1 (0.43) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402790-B1 | SPIROHEPTANE SALICYLAMIDES AND RELATED COMPOUNDS AS INHIBITORS OF ROCK | BRISTOL MYERS SQUIBB CO (US) | 2021-10-06 | — | — | EP | disclosed |