Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22054633 | 0.82 | DHODH (0.40) | DHODHNPY5RATMTNFLMNA | |
| SCHEMBL21297878 | 0.78 | DHODH (0.41) | DHODHATMTNFLMNAACHE | |
| SCHEMBL31194906 | 0.77 | CLK1 (0.42) | DHODHNPY5RLMNAHTTDYRK1A | |
| SCHEMBL24175001 | 0.77 | CLK1 (0.42) | DHODHNPY5RLMNAHTTDYRK1A | |
| SCHEMBL12736849 | 0.74 | LATS1 (0.47) | DHODHLMNAHTTXPO1EGFR | |
| SCHEMBL24996414 | 0.74 | DHODH (0.35) | DHODHNPY5RATMTNFLMNA | |
| SCHEMBL18544725 | 0.74 | LMNA (0.52) | LMNAHTTACHEMAPK10MAOA | |
| SCHEMBL27110226 | 0.72 | TNF (0.35) | DHODHTNFLMNAHTTACHE | |
| SCHEMBL22956798 | 0.72 | CYP1A2 (0.40) | DHODHLMNAACHEHASPINMAPK10 | |
| SCHEMBL19004155 | 0.72 | HIPK2 (0.37) | DHODHATMTNFHTTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889152-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |