Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 4/20 | 0.38 |
| ▸ | JAK1 | P23458 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23889390 | 0.83 | SUV39H2 (0.47) | EIF2AK4SUV39H2 | |
| SCHEMBL22054131 | 0.83 | SUV39H2 (0.47) | EIF2AK4SUV39H2 | |
| SCHEMBL23889388 | 0.83 | TYK2 (0.41) | JAK1JAK2JAK3 | |
| SCHEMBL30227459 | 0.75 | SUV39H2 (0.33) | JAK1JAK2JAK3KMT2ASUV39H2 | |
| SCHEMBL12384778 | 0.72 | BTK (0.59) | BTKJAK1KMT2AL3MBTL1KDM1A | |
| SCHEMBL17915687 | 0.72 | BTK (0.59) | BTKJAK1KMT2AL3MBTL1KDM1A | |
| SCHEMBL12385790 | 0.72 | BTK (0.59) | BTKJAK1KMT2AL3MBTL1KDM1A | |
| SCHEMBL12424495 | 0.72 | BTK (0.59) | BTKJAK1KMT2AL3MBTL1KDM1A | |
| SCHEMBL14176830 | 0.72 | BTK (0.59) | BTKJAK1KMT2AL3MBTL1KDM1A | |
| SCHEMBL15014612 | 0.72 | BTK (0.59) | BTKJAK1KMT2AL3MBTL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889152-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |