SCHEMBL23889656

SCHEMBL23889656

Cc1cnc2c(n1)N(C)CN2

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17813469 0.81 MEN1 (0.44) MEN1RAB9AGFERKMT2A
SCHEMBL18754102 0.72 CRBN (0.42) MEN1KMT2A
SCHEMBL17813459 0.72 MTOR (0.37)
SCHEMBL7923054 0.69 HRH4 (0.33) RAB9AKMT2A
SCHEMBL7914437 0.68 CCR1 (0.31)
SCHEMBL23889253 0.68
SCHEMBL29673365 0.67 SMN1; SMN2 (0.35)
SCHEMBL14643852 0.64 UHRF1 (0.34)
SCHEMBL7922276 0.64 CCR1 (0.31)
SCHEMBL19417814 0.63 HRH4 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3889152-A1 HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) 2021-10-06 EP disclosed