Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3327236 | 1.00 | MAPT (0.60) | MAPTKDM4EALDH1A1SMN1; SMN2TNFRSF1A | |
| SCHEMBL26750820 | 0.89 | MAOB (0.54) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8686533 | 0.85 | MAPT (0.65) | MAPTKDM4EALDH1A1SMN1; SMN2TNFRSF1A | |
| SCHEMBL5574666 | 0.84 | FDPS (0.56) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2690713 | 0.84 | FDPS (0.56) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14143629 | 0.84 | BACE1 (0.69) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17722573 | 0.84 | MAOB (0.60) | KDM4EALDH1A1SMN1; SMN2CYP3A4MAOB | |
| SCHEMBL7111822 | 0.83 | FDPS (0.55) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7111819 | 0.83 | FDPS (0.55) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2537052 | 0.83 | TTR (0.58) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615514-B1 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS INC (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-3567028-B1 | BIPHENYL COMPOUND AS CCR2/CCR5 RECEPTOR ANTAGONIST | MEDSHINE DISCOVERY INC (CN) | 2022-01-05 | — | — | EP | disclosed |
| EP-3567028-A1 | BIPHENYL COMPOUND AS CCR2/CCR5 RECEPTOR ANTAGONIST | Medshine Discovery Inc. (CN) | 2019-11-13 | — | — | EP | disclosed |
| US-20120321533-A1 | CATALYST | ALMQVIST FREDRIK (SE) | 2012-12-20 | — | — | US | disclosed |
| US-20120321533-A1 | CATALYST | ALMQVIST FREDRIK (SE) | 2012-12-20 | — | — | US | disclosed |
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100119424-A1 | CATALYST | ALMQUEST AB (SE) | 2010-05-13 | — | — | US | disclosed |
| WO-2008138938-A2 | PROCESS FOR THE PRODUCTION OF PALLADIUM SUPPORTED CATALYSTS FOR CATALYZING HECK, SUZUKI-MIYAURA SONOGASHIRA COUPLING AND BUCHWALD-HARTWIG REACTIONS | NORDIC CHEMQUEST AB (SE) | 2008-11-20 | — | — | WO | disclosed |