Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 20/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 11/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22039716 | 0.92 | EP300 (0.50) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL22039746 | 0.92 | EP300 (0.50) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL23891727 | 0.87 | EP300 (0.45) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL24350741 | 0.87 | EP300 (0.46) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL22040146 | 0.87 | EP300 (0.47) | EP300CREBBPGABRA1TMEM97DRD3 | |
| SCHEMBL23891742 | 0.83 | TSHR (0.34) | EP300CREBBPGABRA1TMEM97CYP3A4 | |
| SCHEMBL22039751 | 0.83 | EP300 (0.68) | EP300CREBBPGABRA1TMEM97CYP3A4 | |
| SCHEMBL23891796 | 0.83 | EP300 (0.68) | EP300CREBBPGABRA1TMEM97CYP3A4 | |
| SCHEMBL23891533 | 0.83 | EP300 (0.68) | EP300CREBBPGABRA1TMEM97CYP3A4 | |
| SCHEMBL23891729 | 0.81 | EP300 (0.33) | EP300CREBBPGABRA1TMEM97DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |